The fund suffered from poor-performing stocks and markdowns of private holdings.
Little-known Karthik Sarma appeared near the top of this ranking of hedge fund earners.
One of the stocks that likely hurt Tiger's results is Beijing-based retail giant JD.com.
The firm's flagship multistrategy Composite Fund rose 18.5% on the year.
A record number of companies debuted on U.S. exchanges in 2021.
The real danger may be the combination of rising prices and a stagnating economy, Jensen said.
The hedge fund manager also said working outside the office hinders innovation.
While most hedge funds have emerged unscathed, a few were seriously impacted by the Reddit short squeeze movement.
Fed officials surprised markets last week by accelerating their timeline for potential interest-rate increases.
Oil stocks are cheap, and oil will also face supply issues, said the billionaire businessman.