Every good makeup artist knows that the smallest touches can make a world of difference.

For the past 25 years, MAC Cosmetics has been selling its Viva Glam lipstick to raise money for the fight against HIV and AIDS. The subsidiary of Estee Lauder sells the $18.50 lipstick in a mere three shades—bluish-red, pinkish-beige, and brownish-plum—but donates 100% of the proceeds to the cause. Each year, those tiny wands of color generate from $20 million to $30 million; to date, the campaign has raised more than $500 million. The MAC Viva Glam Fund has used the money to deliver nearly 10,000 grants to 1,800 or so different programs around the world.

Now, after 25 years in operation, Viva Glam plans to expand its mandate. It will inject money into underserved communities, including the LGBTQ community and that of vulnerable women and girls. Meanwhile, the fund has also approved a three-year, $1.5 million grant for Unicef that will go to treatment programs for mothers living with HIV in various countries.

MAC Cosmetics debuted Viva Glam in 1994, with its first campaign led by drag queen RuPaul. The MAC business as a whole is now a billion-dollar brand and a major division of an international beauty company. But Viva Glam has endured, continuing to draw shoppers with celebrity-led advertising campaigns.

“I had no clue or expectation that this would have gone as big as it has,” says John Demsey, the executive group president of Estee Lauder who oversees MAC and the fund. “I hope that day comes that the money's not needed for HIV. But I know that, even today, if there was a cure, a charitable organization would need to exist to ensure that the medication and the services got to people who would never be able to afford it.”

Sales of Viva Glam fluctuate, depending on the hype built by its celebrity campaigns. Over the years, ambassadors have included such names as Lady Gaga, Miley Cyrus, Rihanna, Christina Aguilera, and Lil’ Kim. The label’s biggest year ever was led by pop singer Ariana Grande in 2016 as she was releasing her third studio album. Ads had her squeezed into a miniature bedroom showing off limited-edition lipsticks in neutral mauve and orchid pink.

Several of Viva Glam’s previous spokespeople still publicly support the brand. Elton John has called Viva Glam’s method “a wonderful and tangible way to engage people in supporting this critical work.” Chloe Sevigny noted that the personality-driven model has an uncanny knack for attracting eyeballs. “MAC always knows how to put big personalities together to draw attention to this extremely important cause,” she said. Shirley Manson called it a “humble lipstick” that has somehow managed to reach so many people. “Nothing but love, love, love,” she said.

It hasn’t always been easy to get celebrities on board, said Demsey. In some ways, it still isn’t. The celebrities are paid, but Estee Lauder doesn’t spend “a ton” of cash for an endorsement because it’s a charitable endeavor. Many stars didn’t want to have their names connected to such charged subjects, hoping not to alienate fans. They considered it a “career risk,” says Demsey. Executives wouldn’t share which celebrities they’re currently pursuing.

“A degree of piss-off comes with the territory,” says Demsey. “We do have a swagger.”

That was especially evident in March, when MAC took the step of collaborating with Benefit Cosmetics, owned by rival LVMH, and announced its support of Planned Parenthood. It gave a grant to the reproductive health-care nonprofit and took a stand on an issue that was bound to evoke outrage from abortion opponents.

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